Abstract
By the use of water containing an excess over the normal of the heavy oxygen isotope (18O), it has been definitely and very directly shown that during the hydrolysis of the esters of weak carboxylic acids the break occurs at the C—O bond of the ester, thus:
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HERBERT, J., BLUMENTHAL, E. Mechanism of Hydrolysis of Inorganic Esters. Nature 144, 248 (1939). https://doi.org/10.1038/144248a0
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DOI: https://doi.org/10.1038/144248a0
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