Influence of Lactate on the Absorption of Glucose from the Intestine of Adrenalectomized Rats

Article metrics

Abstract

IN experiments designed to throw light on the mechanism of sugar absorption and its control by the adrenal cortex, it was previously found1 that with adrenalectomized rats sodium pyruvate restores the normal sugar absorption from the intestine. Similar experiments using the same methods have now been carried out with sodium lactate which was administered continuously in doses of 15–20 mgm. a day subcutaneously. It was found that it shows the same effect as pyruvate does, restoring the low glucose absorption of the adrenalectomized rats to the normal level. (Normal absorption in forty-five minutes, 80.0 per cent of the injected glucose, with adrenalectomized rats 42.3 per cent, after lactate administration 73.7 per cent.)

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Laszt, L., Verh. schweiz. Physiol., Feb. 1939.

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

LASZT, L. Influence of Lactate on the Absorption of Glucose from the Intestine of Adrenalectomized Rats. Nature 143, 984 (1939) doi:10.1038/143984b0

Download citation

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.