Abstract
IN experiments designed to throw light on the mechanism of sugar absorption and its control by the adrenal cortex, it was previously found1 that with adrenalectomized rats sodium pyruvate restores the normal sugar absorption from the intestine. Similar experiments using the same methods have now been carried out with sodium lactate which was administered continuously in doses of 15–20 mgm. a day subcutaneously. It was found that it shows the same effect as pyruvate does, restoring the low glucose absorption of the adrenalectomized rats to the normal level. (Normal absorption in forty-five minutes, 80.0 per cent of the injected glucose, with adrenalectomized rats 42.3 per cent, after lactate administration 73.7 per cent.)
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Laszt, L., Verh. schweiz. Physiol., Feb. 1939.
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LASZT, L. Influence of Lactate on the Absorption of Glucose from the Intestine of Adrenalectomized Rats. Nature 143, 984 (1939). https://doi.org/10.1038/143984b0
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DOI: https://doi.org/10.1038/143984b0
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