Letter | Published:

Hydrolytic De-amination of Amino-Acids

Nature volume 143, pages 723724 (29 April 1939) | Download Citation

Subjects

Abstract

Virtanen and Erkama1 discovered recently in B. fluorescens liquefaciens an enzyme which causes hydrolysis of aspartic acid into malic acid and ammonia. This, however, is not the first example of hydrolytic de-amination of amino-acids. In a series of papers2, we have been able to show that in aqueous solution, amino-acids are hydrolysed under the influence of ultra-violet light to give the corresponding hydroxy-acids: R.CH(NH2).COOH→R.CH(OH).COOH. Here again, a certain resemblance exists between enzymatic and photochemical processes.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    NATURE, 142, 954 (1938).

  2. 2.

    C.R. Acad. Sci., 198, 168 (1934); J. Amer. Chem. Soc., 58, 1675 (1936); J. Amer. Chem. Soc., 60, 1799 (1938).

  3. 3.

    , "Lehrbuch der Allgemeinen Photochemie", pp. 539, 575 (Berlin and Leipzig, 1920).

  4. 4.

    Chem. Centralblatt, 1, 3126 (1937).

  5. 5.

    , Z. analyt. Chem., 89, 121 (1932).

  6. 6.

    , Biochem. Z., 215, 279 (1929).

  7. 7.

    Clin. Sci., 2, 337 (1936).

Download references

Author information

Affiliations

  1. Daniel Sieff Research Institute, Rehovoth, Palestine. March 23.

    • CH. WEIZMANN
    • , E. BERGMANN
    •  & Y. HIRSHBERG

Authors

  1. Search for CH. WEIZMANN in:

  2. Search for E. BERGMANN in:

  3. Search for Y. HIRSHBERG in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/143723c0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.