Article | Published:

A Derived Patterson Analysis of the Skeleton of the Cyclol C2 Molecule

Nature volume 143, pages 648649 (15 April 1939) | Download Citation

Subjects

Abstract

RECENT publications by Wrinch1, and in particular by Wrinch and Langmuir2, have suggested that the Patterson analyses obtained by Crowfoot3 for air-dried insulin crystals can be interpreted with some precision if one assumes that the basis of the structure of the insulin molecule is the skeleton of the Wrinch cyclol C2. Criticisms of their work were made by Bernal at a recent meeting of the Physical Society and in a recent letter in NATURE,4. We have done the work reported here in order to answer, if possible two questions. How well do the equivalent points chosen by Wrinch and Langmuir represent the cyclol C2structure ? Does the cyclol fabric give a Patterson diagram resembling the one obtained experimentally ? To do this, the separate atoms of the cyclol skeleton were considered and the appropriate Patterson analysis derived from their interatomic vectors.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , J. Amer. Chem. Soc., 60, 2005 and 3099 (1938).

  2. 2.

    , and , J. Amer. Chem. Soc., 60, 2247 (1938).

  3. 3.

    , Proc. Roy. Soc., A, 164, 580 (1938).

  4. 4.

    , NATURE, 143, 74 (1939).

Download references

Author information

Affiliations

  1. Department of Mineralogy, Oxford, and I. Fankuchen, Birkbeck College, London

    • D. P. RILEY

Authors

  1. Search for D. P. RILEY in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/143648a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.