A NEW coupling of oxidoreduction and phosphorylation, with thiamin (vitamin B1) pyrophosphate as a link of the reaction chain, was found with dry preparations of Bacterium Delbrückii (Acidificans longissimum). Phosphorylation of added adenylic acid occurs when pyruvic acid is dehydrogenated, and, as reported previously1, thiamin pyrophosphate is the prosthetic of the enzyme catalysing the dehydrogenation of pyruvic acid.
Lipmann, Enzymologia, 4, 65 (1937).
Lipmann, Sixteenth Internat. Physiol. Congress, Zurich, 1938, Ber., 2, 161.
Meyerhof, Ohlmeyer and Möhle, Biochem. Z., 297, 90 (1938).
Needham and Lu, Biochem. J., 32, 2040 (1938).
Lipmann and Perlmann, J. Amer. Chem. Soc., 60, 2575 (1938).
See review by Williams and Spiess, "Vitamin B1 ", New York (1938).
Birch and Mapson, NATURE, 138, 27 (1936).
Kalckar, NATURE, 142, 871 (1938).
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LIPMANN, F. Biochemistry: Coupling between Pyruvic Acid Dehydrogenation and Adenylic Acid Phosphorylation. Nature 143, 281 (1939). https://doi.org/10.1038/143281a0
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