Letter | Published:

Cyclical Changes in the Adrenal Glands of Spayed Rats

Nature volume 142, page 754 (22 October 1938) | Download Citation



IN an earlier note published in these columns1, it was reported that cyclical variations occur in the responsiveness of the uterus of spayed monkeys to constant œstrogenic stimulation. In view of several considerations, it was suggested in a later communication2 that variations in the size and function of the adrenal cortex, such as occur in normal rats in the œstrous cycle3, may be responsible for these cyclical variations in the uterine response. Later work4 showed that cyclical uterine changes occur in spayed rats as well as in monkeys, and that the adrenal gland is probably concerned in their occurrence5.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    , NATURE, 139, 628 (1937).

  2. 2.

    , and , NATURE, 139, 1106 (1937).

  3. 3.

    , and , J. Physiol., 76, 247 (1932).

  4. 4.

    , J. Physiol., 92, 12 P (1938).

  5. 6.

    , J. Physiol., 92, 13 P (1938).

Download references

Author information


  1. (Beit Memorial Fellow). Department of Human Anatomy, Oxford. Sept. 27.

    • , G. BOURNE
    •  & D. LEWES


  1. Search for S. ZUCKERMAN in:

  2. Search for G. BOURNE in:

  3. Search for D. LEWES in:

About this article

Publication history





By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.