Colchicine and Acenaphthene as Polyploidizing Agents


KOSTOFF1 has recently directed attention to the similarity in action of colchicine and acenaphthene, and recommended the latter substance for purposes of chromosome doubling. Preliminary tests with acenaphthene used in saturated solutions of liquid media2 adapted to the observation of mitosis in stamen hairs of Tradescantia give no indication that acenaphthene is at all comparable to colchicine as a polyploidizing agent. After 2 and 4½ hours, counts of nuclear stages showed the following percentages:

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  1. 1

    Kostoff, D., C.R., U.R.S.S., 19, 197–199 (1938).

  2. 2

    Nebel, B. R., and Ruttle, M. L., J. Heredity, 29, 1–9 (1938).

  3. 3

    Kostoff, NATURE, 141, 1144–1145 (1938).

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NEBEL, B. Colchicine and Acenaphthene as Polyploidizing Agents. Nature 142, 257 (1938).

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