Abstract
SUCCINIC acid has long been known to be oxidized rapidly by muscle and many other tissues. Experiments of Szent-Györgyi and co-workers1 suggested that succinic acid and certain other dicarboxylic acids catalyse the aerobic respiration of muscle tissue. Conclusive proof for this catalysis in muscle tissue was given by Stare and Baumann2, and its application to liver and kidney tissue was shown by Stare3.
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References
Szent-Györgyi, A., and co-workers, Z. physiol. Chem., 236, 1 (1935).
Stare, F. J., and Baumann, C. A., Proc. Roy. Soc., B, 121, 338 (1936).
Stare, F. J., Biochem. J., 30, 2257 (1936).
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STARE, F., GORDON, E. & MUSSER, M. Effect of Succinic Acid on the Respiration of Normal Human Muscle and Various Myopathies. Nature 141, 831 (1938). https://doi.org/10.1038/141831a0
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DOI: https://doi.org/10.1038/141831a0
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