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X-Ray Study of Thymonucleic Acid


A FEW years ago an occasion presented itself of examining by X-rays a small specimen of sodium thymonucleate kindly provided by Prof. W. J. Schmidt1 of Giessen, and an imperfect fibre photograph was obrained with a strong period along the fibre axis of about 3½ A. ; but the observation was not followed up at the time. We have now continued the investigation with material prepared in the Department of Chemistry of the Caroline Institute, Stockholm, by the method of Hammarsten and Bang2. The viscosity and double refraction of flow of this material in aqueous solution were the subject of a recent communication in NATURE by Signer, Caspersson and Hammarsten3.

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  1. 1

    Cf. Schmidt, W. J., "Die Doppelbrecħung von Karyoplasma, Zytoplasma und Metaplasma" (Berlin, 1937).

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  2. 2

    Hammarsten, E., Biochem. Z., 144, 383 (1924).

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  3. 3

    Signer, R., Caspersson, T., and Hammarsten, E., NATURE, 141, 122 (1938).

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  4. 4

    Cf. Astbury, W. T., NATURE, 140, 968 (1937).

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  5. 5

    Cox, E. G., NATURE, 130, 205 (1932). Cox, E. G., and Goodwin, T. H., J. Chem. Soc., 769 (1936).

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ASTBURY, W., BELL, F. X-Ray Study of Thymonucleic Acid. Nature 141, 747–748 (1938).

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