Letter | Published:

Restropic Activity of Blood

Nature volume 141, pages 11001101 (18 June 1938) | Download Citation

Subjects

Abstract

WE have previously described the extraction from the anterior pituitary of two substances that affect the activity of the reticulo-endothelial system1,2,3. One (negative restropic factor) lowers the functional level of the reticulo-endothelial system, the other raises it (positive factor). We have now found that fresh blood (from rabbit or horse) also contains a positive restropic substance. It can be prepared by the methods already applied to extraction of anterior pituitary3. We have not yet found any difference, chemical or biological, between positive restropic extracts from blood and pituitary respectively.

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References

  1. 1.

    NATURE, 140, 149 (July 24, 1937).

  2. 2.

    NATURE, 137, 357 (Feb. 29, 1936).

  3. 3.

    Phys. Rev., 53, 68 (1938).

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Author information

Affiliations

  1. The Laboratory 37 Great Cumberland Place, London, W.1.

    • C. WETZLER-LIGETI
    •  & B. P. WIESNER

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DOI

https://doi.org/10.1038/1411100b0

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