Abstract
IN 1915, Karrer1 put forward the view that the coupling of aromatic tertiary amines with diazo-compounds to form alkylamino azo-compounds takes place through the preliminary combination of the diazo-compound with the nitrogen of the amino group. The experimental basis for this theory was the reported observation that when either di-butylaniline or di-isoamylaniline reacts with diazo-sulphanilic acid, an alkyl group is eliminated with the formation of the corresponding monoalkylamino azobenzene sulphonic acid.
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References
Karrer, Ber., 48, 1398 (1915).
Reilly and Hickinbottom, J. Chem. Soc., 113, 99 (1918).
Hickinbottom, NATURE, 131, 762 (1933).
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HICKINBOTTOM, W., LAMBERT, E. Karrer's Theory of Coupling. Nature 141, 1056 (1938). https://doi.org/10.1038/1411056a0
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DOI: https://doi.org/10.1038/1411056a0
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