Letter | Published:

Histamine and the Action of the Thyroid Gland

Nature volume 141, page 1014 (04 June 1938) | Download Citation



IN previous investigations1 we have pointed out that irradiation of white mice with ultra-violet light is accompanied by a loss of body weight. Furthermore, we have noted2 that there is a relation between the loss of body weight and the function of the thyroid gland. It was possible to demonstrate that the acetonitrile test of Reid Hunt3 becomes positive during the time in which a lowering of body weight of the irradiated mice was found. Because there is a connexion between erythema-producing power of ultra-violet light and the weight loss, the conclusion was drawn that the formation of histamine-like substances seems to be responsible for the activation of the thyroid gland and the loss of body weight.

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  1. 1.

    Radiology, in the press.

  2. 2.

    Skand. Arch. physiol., in the press.

  3. 3.

    Amer. J. Physiol., 63, 257 (1923).

  4. 4.

    Arch. Exp. Pathol. u. Pharmakol., 165, 53 (1932).

  5. 5.

    comp. "Die biologischen Grundlagen der Strahlen-behandlung" (Berlin, 1935).

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  1. Biological Institute, Carlsberg Foundation, Copenhagen. May 7.



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