Abstract
ENOL-ESTERS from the series of male sex hormones were first prepared by L. Ruzicka and W. H. Fischer1, Experiments carried out in our laboratories showed that testosterone diacetate was. less active on the capon's comb than the testosterone monoacetate, but that in single injection (2 mgm.) it was more active than testosterone monoacetate on rats2. Deanesly and Parkes3 recently compared the effect of testosterone monacetate and testosterone diacetate, and the results of their experiments indicated that these In two substances are similar as regards activity. In the meantime, our experiments were extended to the I previously described dipropionate and also to two newly prepared enol-esters of testosterone. The technique corresponds to that earlier described by Miescher, Wettstein and Tschopp4.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Ruzicka, L., and Fischer, W. H., Helv. chim. Acta, 19, 806 (1936).
Ruzicka, L., and Fischer, W. H., Helv. chim. Acta, 19, 1371 (1936).
Deanesly, R., and Parkes, A. S., Biochem. J., 31, 1161 (1937).
Miescher, K., Wettstein, A., and Tschopp, E., Biochem. J., 30, 1970, 1977 (1936).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MIESCHER, K., FISCHER, W. & TSCHOPP, E. The Effect of Enol-Esters of Testosterone. Nature 140, 726–727 (1937). https://doi.org/10.1038/140726a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/140726a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
