Letter | Published:

Sensitization of the Skin of Mice to Light by Carcinogenic Agents

Nature volume 140, page 588 (02 October 1937) | Download Citation

Subjects

Abstract

WHITE mice painted twice a week for three weeks with benzpyrene in benzene are found to be sensitized to light. The mouse is painted and exposed to direct sunlight for a half to one hour ; during the exposure the skin of the painted area becomes red and markedly “dematous. There is no latent period to this reaction ; within a few minutes of the exposure the mouse becomes ill at ease, scratches the painted region and tries to hide it from the sun. The next day, the area shows a definite dermatitis.

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Affiliations

  1. Mount Vernon Hospital, Northwood, Middlesex. Sept. 14.

    • I. DONIACH
    •  & J. C. MOTTRAM

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DOI

https://doi.org/10.1038/140588a0

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