Letter | Published:

Coupling of Dismutations with Esterification of Phosphate in Muscle

Naturevolume 140pages6465 (1937) | Download Citation



THE disappearance of free phosphate during glycogenolysis in muscle extract is a striking phenomenon. One mechanism by which this occurs has recently been elucidated by Parnas and his colleagues1, who showed that, even in long-dialysed extracts, phosphate and glycogen can react together giving hexosemonophosphate. This reaction is poisoned by M/100 phloridzin, but not by M/400 iodoacetic acid. We have observed a second method of phosphate esterification.

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  1. 1

    Parnas and Baranowski, Comptes rend. Soc. Biol., 120, 307 (1935). Ostern, Guthke and Tersakowec, Z. physiol. Chem., 243, 9 (1936). Parnas and Mochnacka, Comptes rend. Soc. Biol., 123, 1173 (1936).

  2. 2

    Meyerhof and Kiessling, Biochem. Z., 281, 449; 283, 83 (1935).

  3. 3

    Schäffner and Berl, Z. physiol. Chem., 238, 111 (1936).

  4. 4

    Dische, Naturwiss., 22, 776 (1934); 24, 462 (1936).

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    Meyerhof and Lehmann, Naturwiss., 23, 337 (1935).

  6. 6

    Parnas and Ostern, Bull. Soc. Chim. Biol., 18, 1471 (1936).

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    Lundsgaard, Biochem. Z., 233, 322 (1931).

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  1. Biochemical Laboratory, Cambridge

    •  & R. K. PILLAI


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