Letter | Published:

Crystallization of Lysozyme

Naturevolume 140page24 (1937) | Download Citation



THE occurrence in nasal mucosa of a substance capable of lysing certain bacteria was noted by Fleming1, and this or a similar compound was later obtained from egg-white by Wolff2 who, however, did not recognize the true chemical nature of the substance. Meyer, Thompson, Palmer and Khorazo3, adopting an entirely different procedure, showed that lysozyme is a protein giving some of the typical reactions ; they also quoted analytical data.

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  1. 1

    Fleming, A., Proc. Roy. Soc., B, 93, 306 (1922).

  2. 2

    Wolff, L. K., Z. Immunitätsforsch., 50, 88 ; 54, 188 (1927).

  3. 3

    Meyer, K., Thompson, R., Palmer, J. W., and Khorazo, D., J. Biol. Chem., 113, 303 (1936).

  4. 4

    Holiday, E. R., Biochem. J., 30, 1795 (1936).

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  1. Dyson Perrins Laboratory, University, Oxford

    • E. P. ABRAHAM
    •  & R. ROBINSON


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