Letter | Published:

Effect of Vitamin E Deficiency on the Thyroid

Nature volume 139, page 286 (13 February 1937) | Download Citation



SINGER1 found that vitamin E deficiency produced hypoplasia of the thyroid in rats. I have noticed what appears to be cretinism in the young of vitamin E-deficient rats. Female rats kept on an E-free diet usually have an initial fertility and produce a litter of living young before becoming absolutely sterile ; the litters of such rats or of rats which have been proved sterile and have then been given a small dose of vitamin E concentrate, just sufficient to produce a litter of two or three, show definite signs of thyroid deficiency.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    J. Physiol., 87, 287 (1936).

Download references

Author information


  1. Physiological Laboratories, The British Drug Houses, Ltd., Graham Street, London, N.1. Jan. 8.

    • M. M. O. BARRIE


  1. Search for M. M. O. BARRIE in:

About this article

Publication history




Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.