Letter | Published:

Effect of Vitamin E Deficiency on the Thyroid

Nature volume 139, page 286 (13 February 1937) | Download Citation

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Abstract

SINGER1 found that vitamin E deficiency produced hypoplasia of the thyroid in rats. I have noticed what appears to be cretinism in the young of vitamin E-deficient rats. Female rats kept on an E-free diet usually have an initial fertility and produce a litter of living young before becoming absolutely sterile ; the litters of such rats or of rats which have been proved sterile and have then been given a small dose of vitamin E concentrate, just sufficient to produce a litter of two or three, show definite signs of thyroid deficiency.

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References

  1. 1.

    J. Physiol., 87, 287 (1936).

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Affiliations

  1. Physiological Laboratories, The British Drug Houses, Ltd., Graham Street, London, N.1. Jan. 8.

    • M. M. O. BARRIE

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DOI

https://doi.org/10.1038/139286a0

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