Abstract
SINGER1 found that vitamin E deficiency produced hypoplasia of the thyroid in rats. I have noticed what appears to be cretinism in the young of vitamin E-deficient rats. Female rats kept on an E-free diet usually have an initial fertility and produce a litter of living young before becoming absolutely sterile ; the litters of such rats or of rats which have been proved sterile and have then been given a small dose of vitamin E concentrate, just sufficient to produce a litter of two or three, show definite signs of thyroid deficiency.
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J. Physiol., 87, 287 (1936).
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BARRIE, M. Effect of Vitamin E Deficiency on the Thyroid. Nature 139, 286 (1937). https://doi.org/10.1038/139286a0
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DOI: https://doi.org/10.1038/139286a0
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