Abstract
I HAVE investigated with the aid of the Warburg technique the action of optically isomeric nicotines upon alcoholic (Torula utilis, Saccharomyces exiguus) and lactic (Bacterium Delbrücki) fermentations of glucose dissolved in the external solution; upon oxidation of exogeneous glucose by T. utilis, S. exiguus, Oidium lactis, Bacillus subtilis, B. mycoides, Sarcina lutea and Bacterium Schützenbachi; upon oxidation of lactate by O. lactis and of ethyl alcohol by B. Schützenbachi; and upon respiration of stored glycogen in T. utilis, S. exiguus and B. subtilis. It was found that in these microbes all fermentations are more strongly depressed by l-nicotine than by d-nicotine, but all oxidations are, conversely, more strongly depressed by d-form.
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References
Warburg et al., Biochem. Z., 282, 157 (1935).
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GAUSE, G. Stereoisomeric Nature of Oxidation and Fermentation. Nature 138, 245–246 (1936). https://doi.org/10.1038/138245c0
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DOI: https://doi.org/10.1038/138245c0
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