Letter | Published:

Chemistry of strogenic Substances

Naturevolume 135page959 (1935) | Download Citation

Subjects

Abstract

IN view of the results published by E. Friedmann in NATURE of April 20, we decided to investigate the effect upon ovariectomised rats of the two compounds specifically mentioned by him as “strogenic, namely, sodium benzylidenepyruvate and sodium furylidene-pyruvate. These were prepared and purified exactly as described by Friedmann1. They were dissolved in water, the strength being 100 mgm. in 3 c.c., and administered in 6 doses of 0·5 c.c., each compound being injected into 5 rats. The technique employed was that described in the paper by Allan, Dickens and Dodds2.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Friedmann, E., Helv. Chim. Acta, 14, 783; 1931.

  2. 2

    Allan, H., Dickens, F., and Dodds, E. C., J. Physiol., 68, 348; 1930.

Download references

Author information

Affiliations

  1. Research Institute, The Cancer Hospital (Free), London, S.W.3

    • J. W. COOK
  2. Courtauld Institute of Biochemistry, Middlesex Hospital, London, W.1

    • E. C. DODDS

Authors

  1. Search for J. W. COOK in:

  2. Search for E. C. DODDS in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/135959b0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.