Abstract
IN a previous letter1 we pointed out that the liver tissues of the rat, rabbit and pigeon are able to synthesise ascorbic acid from mannose in vitro, while those of the guinea pig and monkey are unable to do so. Further experiments indicate that this power is not common to all animals independent of an external supply of ascorbic acid. The liver tissues of the ox, cat and fowl, for example, cannot convert mannose into ascorbic acid in vitro. This might mean either that some other organs in their body are able to effect this transformation or that some entirely different means (for example, bacterial) is employed in these animals for the synthesis of the vitamin.
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Guha and Ghosh, NATURE, 135, 234; Feb. 9, 1935.
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GUHA, B., GHOSH, A. Biological Synthesis of Ascorbic Acid. Nature 135, 871 (1935). https://doi.org/10.1038/135871a0
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DOI: https://doi.org/10.1038/135871a0
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