Possibility of Sedimentation Measurements in Intense Centrifugal Fields

Abstract

THE ultracentrifugal technique worked out in this laboratory enables us to carry out measurements of sedimentation velocity and sedimentation equilibrium in very powerful centrifugal fields1. At the present time, routine work can be done at speeds up to 74,000 r.p.m. with a column of solution 12 mm. in height situated 65 mm. from the centre of rotation. The centrifugal force in this case corresponds to 400,000 times gravity. When it comes to the study of substances of comparatively low molecular weight, for example, 1,000 or 2,000, and when one wishes to make a sedimentation analysis of mixtures of low molecular weight, such as the decomposition products of the proteins, it is of importance to have at one's disposal centrifugal fields of still higher intensity. We have therefore tried to improve our, technique in this direction.

References

  1. 1

    NATURE, 123, 871, June 8, 1929. Chem. Rev., 14, 1; 1934. Science, 79, 327; 1934. Koll.-Z., 67, 1; 1934. Naturwiss., 22, 225; 1934.

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THE SVEDBERG, BOESTAD, G. & ERIKSSON-QUENSEL, I. Possibility of Sedimentation Measurements in Intense Centrifugal Fields. Nature 134, 98 (1934). https://doi.org/10.1038/134098a0

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