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Hexuronic Acid as the Antiscorbutic Factor


WE have reported in a previous note,1 that with a daily dosage of 1 mgm. hexuronic acid guinea-pigs were kept free from symptoms of scurvy for fifty-five days. This experiment was continued to the ninetieth day. During this time all animals receiving hexuronic acid showed normal growth. On the ninetieth day all animals were chloroformed, and on autopsy were found entirely free from scurvy. The animals receiving 1 c.c. of lemon juice showed mild scurvy. The experiment was completed with all the necessary controls.


  1. 1

    NATURE, April 16, p. 576.

  2. 2

    Science, vol. 75, No.1944, April 1, 1932.

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SVIRBELY, J., SZENT-GYöRGYI, A. Hexuronic Acid as the Antiscorbutic Factor. Nature 129, 690 (1932).

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