Structure of the Cell Nucleus

    Article metrics

    Abstract

    IN his presidential address to the Royal Microscopical Society delivered on Jan. 20, Prof. R. Ruggles Gates reviewed present knowledge regarding nuclear structure, especially in relation to genetics. On the basis partly of investigations in his own laboratory, Prof. Gates believes that the nucleolus contains two substances, one of which enters the chromosomes in prophase and leaves them in the telphase of mitosis, and that the chromosome is a double structure throughout the mitotic cycle, a split of the chromonema occurring in metaphase for separation in the following metaphase. The chromonema is derived by the union of chromosomes in prophase, and during interkinesis the chromosome is represented by a double chain of chromomeres. From the evidence of karyomeres in animal cells, the nucleus is regarded as a compound structure, and it was further suggested that the spindle is also compound, the real unit in mitosis being a chromosome with its surrounding karyolymph, which becomes transformed into spindle fibres.

    Rights and permissions

    Reprints and Permissions

    About this article

    Cite this article

    Structure of the Cell Nucleus. Nature 129, 161 (1932) doi:10.1038/129161b0

    Download citation

    Comments

    By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.