News | Published:

Oxidation by Living Cells*

Nature volume 128, pages 175178 (01 August 1931) | Download Citation

Subjects

Abstract

UNTIL recently our knowledge of the chemistry of respiration stopped abruptly at the boundary of the cell. We knew how the oxygen was carried to it in vertebrate blood, and the carbon dioxide carried away. We also knew that the rate of oxygen consumption by the body as a whole, and by certain organs, was a function of numerous variables, such as temperature, hydrogen ion concentration, nervous stimulation, and so on. A certain number of partially oxidised metabolites, such as β-hydroxybutyric acid, had been isolated. But such quantitative knowledge as existed with regard to the details of oxidation was mainly confined to reactions in which coloured molecules were involved: for example, the reduction of methylene blue to a colourless substance, or the oxidation of p-phenylene-diamine to a coloured one.

References

  1. 1.

    , "Uber die katalytische Wirkungen der Iebendigen Substanz", 1926.

  2. 2.

    , Ergeb. Physiol., 20, p. 477; 1922.

  3. 3.

    , Biochem. Jour., 20, p. 703; 1926.

  4. 4.

    , Biochem. Jour., 21, p. 1259; 1927.

  5. 5.

    and , Biochem. Jour., 1924–1928 (Bibliography in Jour. Hyg., 28, p. 139; 1928).

  6. 6.

    , Biochem. Jour., 24, p. 1538; 1930.

  7. 7.

    and , Naturwiss., 19, p. 88; 1931.

  8. 8.

    and , Zeit. physiol. Chem., 192, p. 171; 1930.

  9. 9.

    and , Biochem. Zeit., 202, p. 202; 1928.

  10. 10.

    , , and , Biochem. Jour., 25, p. 534; 1931.

  11. 11.

    , Proc. Roy. Soc, B, 98, p. 312; 1925: 104, p. 236; 1929.

  12. 12.

    and , Biochem. Jour., 20, p. 1138; 1926.

  13. 13.

    , Biochem. Jour., 22, p. 1387; 1928.

  14. 14.

    , "Oxidations et réductions", 1930.

Download references

About this article

Publication history

Published

DOI

https://doi.org/10.1038/128175a0

Authors

  1. Search for J. B. S. HALDANE in:

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing