IT is well known that, for some time past, malaria has been purposely induced as a remedial measure in persons suffering from general paralysis of the insane. The therapeutic value of this proceeding has been placed beyond doubt. Up to 1928, of 2499 patients in institutions in England and Wales so treated, 1188, or 47.5 per cent, were benefited sufficiently to be recorded as ‘recovered’, ‘much improved’, or ‘improved’. Of 656 cases in 1929, 47-7 per cent came under the same heading. The ‘discharged recovered’ numbered nearly 12 per cent, and the ‘discharged relieved’ six or seven per cent. Thus nearly one-fifth of the cases treated by artificial infection with malaria benefit sufficiently to be discharged from hospital.