Abstract
IN recent work Dr. Vera Reader (J. Soc. Chem. ind., 47, 1247; 1928) has found that at least two thermolabile vitamin B factors are necessary for the nutrition of the rat, in addition to the factor or factors supplied by alkaline autoclaved marmite. Proof of these three ‘B’ factors has been made possible by the use of concentrates prepared from baker's yeast by the extended method of Kinnersley and Peters (Bioch. J., 22, 419; 1927), in which the process was carried through to the alcohol stage. These concentrates contain B.1, and are highly curative to the pigeon, but when given to rats in large amounts (up to 8 pigeon doses per diem), they do not supplement completely alkaline autoclaved marmite (pH = 9.0 for 1 hour at 120° C.). The latter contains the thermostable so-called anti-pellagra factor. These facts dispose of any objections raised in a recent paper (Aykroyd and Roscoe, Bioch. J., 23, 493).
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PETERS, R. Vitamin B. Nature 124, 411 (1929). https://doi.org/10.1038/124411a0
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DOI: https://doi.org/10.1038/124411a0
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