Figure 7 | Oncogene

Figure 7

From: Δ9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo

Figure 7

Δ9-Tetrahydrocannabinol (THC) treatment inhibits the xenograft growth of lung tumors in SCID mice. A549 cells (3 × 106) were injected subcutaneously into the right flank of immunodeficient SCID mice. THC was given at a dose of 5 mg/kg/day peritumorally for 21 days (n=6 for each experimental group) after palpable tumors were observed. Tumor size was measured every week. After 3 weeks, significant decreases in tumor volume (a) and tumor weight (b) were observed in the THC-treated animals compared to the vehicle-treated animals (**P<0.001; compared to vehicle-treated animals).

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