Table 2 Upregulation levels of 52-muscle development related genes represented by 67 probe sets

From: Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

Gene name Common Description Rh4 fold change upregulation si versus sc RD fold change upregulation si versus sc
209904_at TNNC1 Troponin C, slow 58.2 0.8
205163_at HUMMLC2B Myosin light chain 2 37.1 0.9
205388_at TNNC2 Troponin C2, fast 34.4 1.0
206304_at MYBPH Myosin binding protein H 22.4 1.0
205940_at MYH3 Myosin, heavy polypeptide 3, skeletal muscle, embryonic 21.6 0.6
206393_at TNNI2 Troponin I, skeletal, fast 18.4 0.8
221994_at PDLIM5 LIM protein (similar to rat protein kinase C-binding enigma) 15.1 0.9
214122_at PDLIM7 PDZ and LIM domain 7 (enigma) 14.2 1.2
210329_s_at SGCD Sarcoglycan, δ (35 kDa dystrophin-associated glycoprotein) 12.6 1.3
209283_at CRYAB Crystallin, αB 9.6 1.0
205951_at MYH1 Myosin, heavy polypeptide 1, skeletal muscle, adult 9.5 5.1
219772_s_at SMPX Small muscle protein, X-linked 8.6 1.1
205730_s_at ABLIM3 Go_function: actin binding (goid 0003779) (evidence IEA); go_process: cytoskeleton organization and biogenesis (goid 0007010) (evidence IEA); Homo sapiens actin binding LIM protein family, member 3 (ABLIM3), mRNA. 8.3 0.9
206394_at MYBPC2 Myosin binding protein C, fast type 7.7 3.9
34471_at MYH8 Myosin, heavy polypeptide 8, skeletal muscle, perinatal 7.4 1.5
213023_at UTRN Utrophin (homologous to dystrophin) 7.2 1.3
205610_at MYOM1 Myomesin 1 (skelemin) 185 kDa 6.3 1.0
206116_s_at TPM1 Tropomyosin 1 (α) 6.2 0.7
209888_s_at MYL1 Myosin, light polypeptide 1, alkali; skeletal, fast 6.1 1.0
200974_at ACTA2 Actin, α2, smooth muscle, aorta 5.9 0.8
218736_s_at PALMD Palmdelphin 5.9 1.1
201438_at COL6A3 Collagen, type VI, α3 5.8 1.2
206538_at MRAS Muscle RAS oncogene homolog 5.6 3.5
210298_x_at FHL1 Four and a half LIM domains 1 5.3 1.0
210395_x_at MYL4 Myosin, light polypeptide 4, alkali; atrial, embryonic 5.3 0.6
216054_x_at MYL4; GT1; ALC1; AMLC; PRO1957 Human MLC1emb gene for embryonic myosin alkaline light chain, promoter and exon 1. 5.2 0.5
205693_at TNNT3 Troponin T3, skeletal, fast 5.1 0.7
210088_x_at MYL4 Myosin, light polypeptide 4, alkali; atrial, embryonic 5.1 0.5
210330_at SGCD Sarcoglycan, δ (35 kDa dystrophin-associated glycoprotein) 5.0 2.1
206717_at MYH8 Myosin, heavy polypeptide 8, skeletal muscle, perinatal 5.0 1.4
217585_at NEBL Nebulette 4.8 1.0
210202_s_at BIN1 Bridging integrator 1 4.6 0.8
205547_s_at TAGLN Transgelin 4.5 0.8
203037_s_at MTSS1 Metastasis suppressor 1 4.2 1.0
207317_s_at CASQ2 Calsequestrin 2 (cardiac muscle) 4.1 1.1
213371_at LDB3 LIM domain binding 3 4.1 0.7
203821_at DTR Diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) 4.0 0.5
214087_s_at MYBPC1 Myosin binding protein C, slow type 4.0 1.0
203243_s_at PDLIM5 LIM protein (similar to rat protein kinase C-binding enigma) 4.0 1.0
205177_at TNNI1 Troponin I, skeletal, slow 3.9 0.7
207302_at SGCG Sarcoglycan, γ (35 kDa dystrophin-associated glycoprotein) 3.9 1.1
204173_at MLC1SA Myosin light chain 1 slow a 3.8 0.9
206117_at TPM1 Tropomyosin 1 (α) 3.5 0.7
201976_s_at MYO10 Myosin X 3.4 1.0
202931_x_at BIN1 Bridging integrator 1 3.3 0.9
214492_at SGCD Sarcoglycan, δ (35 kDa dystrophin-associated glycoprotein) 3.1 1.3
219829_at ITGB1BP2 Integrin β 1 binding protein (melusin) 2 3.1 0.3
217274_x_at MYL4; GT1; ALC1; AMLC; PRO1957 Skeletal embryonic form; H sapiens skeletal embryonic myosin light chain 1 (MLC1) mRNA 2.8 0.7
215279_at SVIL Supervillin 2.7 1.1
213717_at LDB3 LIM domain binding 3 2.6 1.0
204533_at CXCL10 Chemokine (C-X-C motif) ligand 10 2.5 1.2
213022_s_at UTRN Utrophin (homologous to dystrophin) 2.5 1.4
214643_x_at BIN1 Bridging integrator 1 2.5 1.1
201079_at SYNGR2 Synaptogyrin 2 2.5 0.7
222022_at DTX3 Deltex 3 homolog (Drosophila) 2.5 1.2
215222_x_at   Microtubule-actin crosslinking factor 1 2.4 0.8
210201_x_at BIN1 Bridging integrator 1 2.3 0.9
207968_s_at MEF2C MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) 2.3 1.0
209926_at MEF2B MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) 2.2 1.1
209200_at MEF2C MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) 2.2 1.0
219107_at BCAN Brevican 2.2 1.1
216887_s_at LDB3 LIM domain binding 3 2.2 1.0
210360_s_at MTSS1 Metastasis suppressor 1 2.1 0.7
206813_at CTF1 Cardiotrophin 1 2.1 0.8
202222_s_at DES Desmin 2.1 0.7
203004_s_at MEF2D MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) 2.1 0.8
201792_at AEBP1 AE-binding protein 1 2.0 0.9