Figure 5 | Oncogene

Figure 5

From: Gene expression analysis of early and advanced gastric cancers

Figure 5

ISH-TMA analysis of epithelial-specific genes in normal mucosa, high-grade dysplasia and invasive carcinomas. Serial TMA sections of normal, high-grade dysplasia, and invasive tumor areas of the same EGC and AGC samples of two representative patients (two EGC and two AGC) are shown. Expression levels of the epithelial-associated TFF2 and CLDN18 genes (black/brown signal in bright field; silver grain signal in dark field) varied according to the tissue-type and gene studied, sometimes totally obscuring the underlining cell morphology. Normal: normal gastric mucosa; dysplasia: high grade dysplasia; invasive: invasive gastric carcinoma.

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