Figure 7 | Oncogene

Figure 7

From: DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis

Figure 7

DSG3 knockdown reduces cell migration in three HNC cell lines. After transfection of either DSG3-RNAi or the vector plasmids, 2 × 106 transfectants were seeded per well in a six-well fibronectin-coated plate and incubated for 6 h to allow monolayer cell formation. Cells were wounded by a micropipette tip and then incubated in the presence of 1% FBS culture medium for 24 h. Cell migration toward the wounded area was observed and photographed.

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