Figure 2 | Oncogene

Figure 2

From: Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells

Figure 2

Resveratrol sensitizes resistant colon cancer cells to death receptor ligands. HT29 and HCT116 cells were either left untreated (Co) or treated for 48 h with 10 (R10) or 30 (R30) μ M resveratrol. When indicated, CH11 (100 ng/ml with 0.8 μg/ml of cycloheximide) or TNFα (25 ng/ml) or TRAIL (100 ng/ml with 2 μg/ml enhancer) was added to the culture medium for the last 24 h. The percentage of cells with a condensed nuclear chromatin, as identified by Hoechst 33342 staining, was measured at the end of cell treatment (mean±s.d. of three independent experiments; 300 cells/point)

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