Figure 4 | Oncogene

Figure 4

From: ΔMEKK3:ER* activation induces a p38α/β2-dependent cell cycle arrest at the G2 checkpoint

Figure 4

Activation of ΔMEKK3:ER* induces cell cycle arrest and apoptosis. Asynchronous CM3.3 cells were treated with 100 nM 4-HT for up to 35 h. Cells were fixed and stained with propidium iodide before their cell cycle profiles were analysed by flow cytometry. Representative histograms of number of cells versus DNA content are displayed. The corresponding percentage of cells in each phase of the cell cycle was quantified and is displayed in Table 1. Similar results were observed in up to six independent experiments in all three clones

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