Figure 7 | Oncogene

Figure 7

From: Inhibition of Bcl-xL expression sensitizes normal human keratinocytes and epithelial cells to apoptotic stimuli

Figure 7

Induction of apoptosis of hKn and A549 cells treated with UV-B radiation. (a) hKn cells were transfected with no oligonucleotide, 300 nM Bcl-xL antisense inhibitor (ISIS 16009), or 300 nM control (ISIS 20292) oligonucleotide. Twenty-four hours after transfection, cells were treated with the indicated level of UV-B radiation. Twenty-four hours after UV-B exposure, cells were harvested and analysed for apoptosis as described in the Materials and methods. (b) A549 cells were transfected with no oligonucleotide, 50 nM Bcl-xL antisense inhibitor (ISIS 16009), or 50 nM control (ISIS 20292) oligonucleotide and treated as described above. The results shown are representative of three independent experiments

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