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The Chemistry of the Adrenal Cortex

Abstract

IN a previous paper (Biochem. Z., 181, 433; 1927) it was shown that extracts of the adrenal cortex strongly reduce silver nitrate and iodine. This reduction could not be accounted for either by adrenalin or glutathione, and seemed to be specific to the interrenal tissue. To exclude any anticipation of function and chemical structure, the substance giving this reduction was named by its protocol-number “Cxii,” being the twelfth substance prepared and examined in my work on tissue oxidation and the function of the adrenal cortex. Having been enabled to resume this work at the Biochemical Laboratory, Cambridge, the substance has been further investigated and finally isolated in crystals, which on recrystallisation showed a constant melting-point.

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SZENT-GYÖRGYI, A. The Chemistry of the Adrenal Cortex. Nature 119, 782–783 (1927). https://doi.org/10.1038/119782c0

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