Genes and Linkage Groups in Genetics

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I FIND it a little difficult to deal with Prof. MacBride's reply to my letter, in NATURE of December 26, since it seems to me not to take any account of the numerous facts bearing on the point which I raised. I feel that the only course is very briefly to enumerate the chief of these facts, and leave other biologists to judge if Prof. MacBride is right in his strictures, or in his views of linkage. I do this at the risk of becoming tedious, because it appears to me very unfortunate that, when delicate quantitative methods are at length introduced into a difficult biological field, they should be attacked on what I consider wholly insufficient grounds by prominent authorities such as Prof. MacBride.

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