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Home blood pressure measurements associated with better blood pressure control: the J-HOME study

Journal of Human Hypertension volume 22, pages 197–204 (2008)Cite this article

Abstract

The usefulness of self-measurements of blood pressure (BP) at home (home BP measurements) in hypertensive patients has been reported by many studies. Several national guidelines recommend the use of home BP measurements to achieve better hypertension control. The objective of this study was to clarify the association between home BP measurements and hypertension treatment among 2363 essential hypertensive patients taking antihypertensive drugs. Compared to the 543 (23.0%) patients who had not taken home BP measurements, the 1820 (77.0%) patients who had taken home BP measurements were significantly older, included a higher proportion of males, included a higher proportion with a family history of hypertension, took a greater number of antihypertensive drugs and alpha blockers and took antihypertensive drugs more often in the evening. Home BP measurements were associated with significantly better control of home and office BP levels. Compared to patients who had not taken home BP measurements, the adjusted odds ratios for good control of morning home BPs, evening home BPs and office BPs in patients who had taken home BP measurements were 1.46 (95% confidential interval (CI) 1.33–1.57), 1.35 (95% CI 1.21–1.47) and 1.23 (95% CI 1.06–1.37), respectively. Home BP measurements were associated with good hypertensive management. Our findings suggest that it is important that physicians recommend home BP measurements to their patients.

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Acknowledgements

This work was supported by Grants for Scientific Research (15790293, 1654041 and 1854042) from the Ministry of Education, Culture, Sports, Science and Technology, Health Science Research Grants on Health Services (13072101, H12-Medical Care-002) from the Ministry of Health, Labour and Welfare and by Nouvelle Place Inc., Japan. The study was designed, conducted and interpreted by the investigators independent of the sponsors. This study was conducted by the J-HOME Study Group.

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Author notes

  1. Y Imai: See Appendix.

Authors and Affiliations

  1. Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Medicine, Sendai, Japan

    T Obara, M Kikuya, T Kato, A Hara, K Totsune & Y Imai

  2. Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan

    T Ohkubo, K Tanaka & J Hashimoto

  3. Tohoku University 21st Century COE Program ‘Comprehensive Research and Education Center for Planning of Drug Development and Clinical Evaluation’, Sendai, Japan

    T Obara, T Ohkubo, K Asayama, R Inoue, A Hara, J Hashimoto, K Totsune & Y Imai

  4. Department of Medical Genetics, Tohoku University Graduate School of Medicine, Sendai, Japan

    H Metoki

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  1. T Obara
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the J-HOME Study Group

Corresponding author

Correspondence to T Ohkubo.

Appendix

Appendix

Members of the J-HOME Study Group

Principal investigator

Yutaka Imai

Advisory committee

Masatoshi Fujishima (deceased), Takao Saruta

Steering Committee

Toshio Ogihara, Kazuaki Shimamoto, Toshiro Fujita, Kazuyuki Shimada, Toshio Ikeda, Iwao Kuwajima, Satoru Kuriyama, Kazuomi Kario

Coordinating and data management centre

Takayoshi Ohkubo, Taku Obara, Masahiro Kikuya, Kei Asayama, Hirohito Metoki, Kayo Murai, Rie Komai, Testuo Kato, Koji Tanaka, Tsuyoshi Horikawa, Azusa Hara, Takuya Oikawa, Kazuhito Totsune, Junichiro Hashimoto

The names of all participating practitioners have been previously published.16

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Obara, T., Ohkubo, T., Asayama, K. et al. Home blood pressure measurements associated with better blood pressure control: the J-HOME study. J Hum Hypertens 22, 197–204 (2008). https://doi.org/10.1038/sj.jhh.1002320

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