Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Commentary
  • Published:

Coffee and health: explaining conflicting results in hypertension

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Dickinson HO, Mason JM, Nicolson DJ, Campbell F, Beyer FR, Cook JV et al. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials. J Hypertens 2006; 24: 215–233.

    Article  CAS  PubMed  Google Scholar 

  2. Bertrand CA, Pomper I, Hillman G, Duffy JC, Micheli I . No relation between coffee and blood pressure. N Engl J Med 1978; 299: 315–316.

    Article  CAS  PubMed  Google Scholar 

  3. Nurminen ML, Niittynen L, Korpela R, Vapaatalo H . Coffee, caffeine and blood pressure: a critical review. Eur J Clin Nutr 1999; 53: 831–839.

    Article  CAS  PubMed  Google Scholar 

  4. Winkelmayer WC, Stampfer MJ, Willett WC, Curhan GC . Habitual caffeine intake and the risk of hypertension in women. JAMA 2005; 294: 2330–2335.

    Article  CAS  PubMed  Google Scholar 

  5. Klag MJ, Wang NY, Meoni LA, Brancati FL, Cooper LA, Liang KY et al. Coffee intake and risk of hypertension: the Johns Hopkins precursors study. Arch Intern Med 2002; 162: 657–662.

    Article  PubMed  Google Scholar 

  6. Jee SH, He J, Whelton PK, Suh I, Klag MJ . The effect of chronic coffee drinking on blood pressure: a meta-analysis of controlled clinical trials. Hypertension 1999; 33: 647–652.

    Article  CAS  PubMed  Google Scholar 

  7. Noordzij M, Uiterwaal CS, Arends LR, Kok FJ, Grobbee DE, Geleijnse JM . Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens 2005; 23: 921–928.

    Article  CAS  PubMed  Google Scholar 

  8. Sudano I, Spieker L, Binggeli C, Ruschitzka F, Luscher TF, Noll G et al. Coffee blunts mental stress-induced blood pressure increase in habitual but not in nonhabitual coffee drinkers. Hypertension 2005; 46: 521–526.

    Article  CAS  PubMed  Google Scholar 

  9. Boos CJ, Lip GY . Elevated high-sensitive C-reactive protein, large arterial stiffness and atherosclerosis: a relationship between inflammation and hypertension? J Hum Hypertens 2005; 19: 511–513.

    Article  CAS  PubMed  Google Scholar 

  10. Tsioufis C, Dimitriadis K, Vasiliadou C, Taxiarchou E, Vezali E, Tsiamis E et al. Heavy coffee consumption in conjunction with smoking is accompanied by increased inflammatory processes and impaired thrombosis/fibrinolysis system in essential hypertensive subjects. J Hum Hypertens 2006; 20: 470–472.

    Article  CAS  PubMed  Google Scholar 

  11. Zampelas A, Panagiotakos DB, Pitsavos C, Chrysohoou C, Stefanadis C . Associations between coffee consumption and inflammatory markers in healthy persons: the ATTICA study. Am J Clin Nutr 2004; 80: 862–867.

    Article  CAS  PubMed  Google Scholar 

  12. Svilaas A, Sakhi AK, Andersen LF, Svilaas T, Strom EC, Jacobs Jr DR et al. Intakes of antioxidants in coffee, wine, and vegetables are correlated with plasma carotenoids in humans. J Nutr 2004; 134: 562–567.

    Article  CAS  PubMed  Google Scholar 

  13. van Dam RM, Hu FB . Coffee consumption and risk of type 2 diabetes: a systematic review. JAMA 2005; 294: 97–104.

    Article  CAS  PubMed  Google Scholar 

  14. Andersen LF, Jacobs Jr DR, Carlsen MH, Blomhoff R . Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa Women's Health Study. Am J Clin Nutr 2006; 83: 1039–1046.

    Article  CAS  PubMed  Google Scholar 

  15. Vlachopoulos C, Panagiotakos D, Ioakeimidis N, Dima I, Stefanadis C . Chronic coffee consumption has a detrimental effect on aortic stiffness and wave reflections. Am J Clin Nutr 2005; 81: 1307–1312.

    Article  CAS  PubMed  Google Scholar 

  16. Suzuki A, Fujii A, Yamamoto N, Yamamoto M, Ohminami H, Kameyama A et al. Improvement of hypertension and vascular dysfunction by hydroxyhydroquinone-free coffee in a genetic model of hypertension. FEBS Lett 2006; 580: 2317–2322.

    Article  CAS  PubMed  Google Scholar 

  17. Suzuki A, Yamamoto N, Jokura H, Yamamoto M, Fujii A, Tokimitsu I et al. Chlorgenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats. J Hypertens 2006; 24: 1065–1073.

    Article  CAS  PubMed  Google Scholar 

  18. Funatsu K, Yamashita T, Nakamura H . Effect of coffee intake on blood pressure in male habitual alcohol drinkers. Hypertens Res 2005; 28: 521–527.

    Article  PubMed  Google Scholar 

  19. Woodward M, Tunstall-Pedoe H . Coffee and tea consumption in the Scottish Heart Health Study follow up: conflicting relations with coronary risk factors, coronary disease, and all cause mortality. J Epidemiol Commun Health 1999; 53: 481–487.

    Article  CAS  Google Scholar 

  20. Urgert R, Katan MB . The cholesterol-raising factor from coffee beans. Annu Rev Nutr 1997; 17: 305–324.

    Article  CAS  PubMed  Google Scholar 

  21. Lopez-Garcia E, van Dam RM, Willett WC, Rimm EB, Manson JE, Stampfer MJ et al. Coffee consumption and coronary heart disease in men and women. A prospective cohort study. Circulation 2006; 113: 2045–2053.

    Article  PubMed  Google Scholar 

  22. Cornelis MC, El-Sohemy A, Kabagambe EK, Campos H . Coffee, CYP1A2 Genotype, and risk of myocardial infarction. JAMA 2006; 295: 1135–1141.

    Article  CAS  PubMed  Google Scholar 

  23. Jessani S, Watson T, Cappuccio FP, Lip GY . Prevention of cardiovascular disease in clinical practice: The Joint British Societies' (JBS 2) guidelines. J Hum Hypertens 2006; doi:10.1038/sj.jhh.1002058.

    Article  CAS  PubMed  Google Scholar 

  24. Williams B, Poulter NR, Brown MJ, Davis M, McInnes GT, Potter JF et al. British Hypertension Society. Guidelines for management of hypertension: report of the fourth working party of the British Hypertension Society, 2004-BHS IV. J Hum Hypertens 2004; 18 (3): 139–185.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M Hamer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hamer, M. Coffee and health: explaining conflicting results in hypertension. J Hum Hypertens 20, 909–912 (2006). https://doi.org/10.1038/sj.jhh.1002076

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.jhh.1002076

This article is cited by

Search

Quick links