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Gender-related differences in left ventricular structural and functional responses to hypertension

Journal of Human Hypertension volume 19, pages 915–917 (2005)Cite this article

As a response to pressure overload, females predominantly develop concentric remodelling, while an eccentric pattern is observed in men.1, 2, 3 It remains unknown, however, whether hypertensive females are more prone to diastolic dysfunction than male patients. We therefore compared echocardiographic diastolic function, brain natriuretic peptide, and ventricular geometry in 177 male and female untreated elderly hypertensive patients.

Elderly patients aged between 60 and 75 years with untreated essential hypertension (⩾160/95 mmHg) were recruited from a population survey according to a previously described protocol.4 All subjects had sinus rhythm. The study was approved by the Medical Ethical Committee of the University Medical Center Groningen, The Netherlands, and written informed consent was obtained.

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Authors and Affiliations

  1. Department of Cardiology, Thoraxcenter, University Medical Center Groningen, Groningen, The Netherlands

    A A Voors, W F Terpstra & D J van Veldhuisen

  2. Department of Internal Medicine, University Medical Center Groningen, Groningen, The Netherlands

    A J Smit & P A de Graeff

  3. Department of General Practice, University Medical Center Groningen, Groningen, The Netherlands

    F W Beltman

  4. Department of Cardiology, Refaja Hospital, Stadskanaal, The Netherlands

    R Vijn

Authors
  1. A A Voors
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  2. W F Terpstra
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  3. A J Smit
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  4. F W Beltman
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  5. R Vijn
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  6. P A de Graeff
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  7. D J van Veldhuisen
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Correspondence to A A Voors.

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Voors, A., Terpstra, W., Smit, A. et al. Gender-related differences in left ventricular structural and functional responses to hypertension. J Hum Hypertens 19, 915–917 (2005). https://doi.org/10.1038/sj.jhh.1001908

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