Abstract
New onset of seizures in young adults is frequently related to alcohol withdrawal, toxic exposure, central nervous system trauma and neoplasm. We describe a young soldier presenting to the emergency department with seizures and transient coma. On admission, he had hypertension, marked leukocytosis, hyper-glycaemia, acidosis, elevated creatinine and elevated creatine phosphokinase of muscle origin. A thorough work-up revealed elevated urinary catecholamines, and a left adrenal mass was found on MRI and MIBG scan. The patient underwent laparoscopic adrenalectomy and completely recovered. This is the first description of seizures as a presenting symptom of phaeochromo-cytoma.
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References
Mosewich RK, So EL . A clinical approach to the classification of seizures and epileptic syndromes. Mayo Clin Proc 1996; 71: 405–414.
Kebebew E, Duh QY . Benign and malignant pheochromo-cytoma: diagnosis, treatment, and follow-up. Surg Oncol Clin N Am 1998; 7: 765–789.
Walther MM, Keiser HR, Linehan WM . Pheochromocytoma: evaluation, diagnosis, and treatment. World J Urol 1999; 17: 35–39.
Lehmann FS, Weiss P, Ritz R, Harder F, Staub JJ . Reversible cerebral ischemia in patients with pheochromocytoma. J Endocrinol Invest 1999; 22: 212–214.
Scardigli K, Biller J, Brooks MH, Cespedes LE, Posniak HV . Pontine hemorrhage in a patient with pheochromo-cytoma. Arch Intern Med 1985; 145: 343–344.
Eclavea A et al. Phaeochromocytoma with central nervous system manifestations. Australas Radiol 1997; 41: 373–376.
Grossman E et al. Uncommon presentation of pheo-chromocytoma: case studies. Angiology 1985; 36: 759–765.
Jadoul M et al. Pheochromocytoma-induced hyper-tensive encephalopathy revealing MEN-IIa syndrome in a 13-year old boy. Implications for screening procedures and surgery. Horm Metab Res Suppl 1989; 21: 46–49.
Roberts AH . Association of a phaeochromocytoma and cerebral gliosarcoma with neurofibromatosis. Br J Surg 1967; 54: 78–79.
Lo CY, Lam KY, Wat MS, Lam KS . Adrenal pheochromocytoma remains a frequently overlooked diagnosis. Am J Surg 2000; 179: 212–215.
Metz SA, Halter JB, Porte, Jr D, Robertson RP . Autonomic epilepsy: clonidine blockade of paroxysmal catecholamine release and flushing. Ann Intern Med 1978; 88: 189–193.
Meyers DH . Association of phaeochromocytoma and prolactinoma. Med J Aust 1982; 1: 13–14.
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Leiba, A., Bar-Dayan, Y., Leker, R. et al. Seizures as a presenting symptom of phaeochromocytoma in a young soldier. J Hum Hypertens 17, 73–75 (2003). https://doi.org/10.1038/sj.jhh.1001499
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DOI: https://doi.org/10.1038/sj.jhh.1001499