Table 3 Genetic correlation (ρg) of adiposity traits with apnea hypopnea index

From: Shared genetic basis for obstructive sleep apnea and adiposity measures

  Home sample GCRC sample GCRC sample with BMI adjustment
  ρg H0: ρg=0 H0: ρg=1 ρg H0: ρg=0 H0: ρg=1 ρg H0: ρg=0 H0: ρg=1
Body mass index 0.59 (0.06) P<10−10 P<10−10 0.64 (0.09) P<10−5 P<10−5
Waist 0.61 (0.06) P<10−10 P<10−10 0.67 (0.09) P<10−5 P<10−4 0.22 (0.18) P=0.22 P<10−4
Hip 0.57 (0.06) P<10−10 P<10−10 0.61 (0.10) P<10−5 P<10−5 −0.06 (0.19) P=0.77 P<10−5
Neck 0.59 (0.06) P<10−10 P<10−10 0.56 (0.10) P<10−4 P<10−6 0.05 (0.16) P=0.73 P<10−5
Leptin     0.46 (0.16) P=0.015 P<10−3 −0.43 (0.36) P=0.20 P=0.80
Adiponectin     −0.34 (0.13) P=0.012 P<10−7 −0.15 (0.15) P=0.32 P<10−5
Resistin     0.11 (0.13) P=0.41 P<10−7 0.01 (0.14) P=0.92 P<10−5
  1. Abbreviations: BMI, body mass index; GCRC, general clinical research center; ρg, genetic correlation.
  2. Maximum likelihood estimates are displayed with standard errors in parentheses.
  3. All models include age, age2, sex, age × sex and height as covariates.