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  • Original Article
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Energy replacement attenuates the effects of prior moderate exercise on postprandial metabolism in overweight/obese men

International Journal of Obesity volume 32, pages 481–489 (2008)Cite this article

Abstract

Background:

The extent to which exercise-induced changes to postprandial metabolism are dependant on the associated energy deficit is not known.

Objective:

To determine the effects of exercise, with and without energy replacement, on postprandial metabolism.

Design:

Each subject underwent three 2-day trials in random order. On day 1 of each trial subjects rested (control), walked at 50% maximal oxygen uptake to induce a net energy expenditure of 27 kJ kg−1 body mass (energy-deficit) or completed the same walk with the net energy expended replaced (energy-replacement). On day 2 subjects completed an 8.5-h metabolic assessment. For 3 days prior to day 2, subjects consumed an isocaloric diet, avoided planned exercise (apart from exercise interventions) and alcohol.

Subjects:

A total of 13 overweight/obese men (age: 40±8 years, body mass index: 31.1±3.0 kg m−2).

Measurements:

Postprandial triglyceride, insulin, glucose, non-esterified fatty acid and 3-hydroxybutyrate concentrations and substrate utilization rates were determined.

Results:

Energy-deficit lowered postprandial triglyceride concentrations by 14 and 10% compared with control and energy-replacement (P<0.05 for both). Energy-deficit increased postprandial 3-hydroxybutyrate concentrations by 40 and 19% compared with control and energy-replacement (P<0.05 for both). Postprandial insulin concentrations were 18 and 10% lower for energy-deficit and energy-replacement compared with control and 10% lower for energy-deficit than energy-replacement (P<0.05 for all). Postprandial fat oxidation increased by 30 and 14% for energy-deficit and energy-replacement compared to control and was 12% higher for energy-deficit than energy-replacement (P<0.05 for all).

Conclusion:

Exercise with energy replacement lowered postprandial insulinaemia and increased fat oxidation. However an exercise-induced energy deficit augmented these effects and was necessary to lower postprandial lipaemia.

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Acknowledgements

This work was supported by TENOVUS Scotland. We thank Dr Nicholas Barwell for clinical assistance with subject screening and on experimental study days.

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Authors and Affiliations

  1. Institute of Diet, Exercise and Lifestyle, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, UK

    F L Burton, D Malkova & J M R Gill

  2. Section of Vascular Biochemistry, University of Glasgow, Glasgow, UK

    M J Caslake

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  1. F L Burton
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  2. D Malkova
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Correspondence to J M R Gill.

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Burton, F., Malkova, D., Caslake, M. et al. Energy replacement attenuates the effects of prior moderate exercise on postprandial metabolism in overweight/obese men. Int J Obes 32, 481–489 (2008). https://doi.org/10.1038/sj.ijo.0803754

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