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Beverages and positive energy balance: the menace is the medium

Abstract

Energy-containing beverages have been implicated in the increasing incidence and prevalence of overweight and obesity. This association has been challenged based on some conflicting evidence and questions about a plausible mechanism. However, the preponderance of epidemiological data indicates that caloric beverage consumption is positively associated with energy intake and body mass index, and this is supported by most intervention trials. Mechanistic questions remain largely unresolved, but there is compelling evidence that caloric beverages elicit weak satiety and compensatory dietary responses. Some attribute this to the components of beverages (e.g., carbohydrate form), but the totality of evidence indicates that the limited appetitive and dietary responses hold across beverage types. This suggests that the fluid medium rather than energy form or nutrient composition is responsible. If true, this hypothesis holds implications for recommendations to the moderate consumption of energy from beverages for example, substitution of one energy-yielding beverage for another may be less effective than reducing intake or switching to lower or non-energy sources.

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References

  1. Block G . Foods contributing to energy intake in the US: data from NHANES III and NHANES 1999–2000. J Food Comp Anal 2004; 17: 439–447.

    Google Scholar 

  2. Putnam J, Allshouse JE . Food consumption, prices and expenditures, 1970–97. US Department of Agriculture Economic Research Service statistical bulletin no. 965, April. US Government Printing Office: Washington, DC, 1999.

  3. Popkin BM, Armstrong LE, Bray GM, Caballero B, Frei B, Willett WC . A new proposed guidance system for beverage consumption in the United States. Am J Clin Nutr 2006; 83: 529–542.

    CAS  PubMed  Google Scholar 

  4. Shields DH, Corrales KM, Metallinos-Katsaras E . Gourmet coffee beverage consumption among college women. J Am Diet Assoc 2004; 104: 650–653.

    PubMed  Google Scholar 

  5. De Castro JM . The effects of the spontaneous ingestion of particular foods or beverages on the meal pattern and overall nutrient intake of humans. Physiol Behav 1993; 53: 1133–1144.

    CAS  PubMed  Google Scholar 

  6. Hill AJ . The effect of dietary composition on hunger, satiation and satiety. Progress in Obesity Research:8. In: Guy-Grand and Ailhaud G, (eds). John Libbey & Co. 1999/8th International Congress on Obesity, 1999; 209–213.

  7. Booth DA, Chase A, Campbell AT . Relative effectiveness of protein in the late stages of appetite suppression in man. Physiol Behav 1970; 5: 1299–1302.

    CAS  PubMed  Google Scholar 

  8. Hill AJ, Blundell JE . Macronutrients and satiety: the effects of a high-protein or high-carbohydrate meal on subjective motivation to eat and food preferences. Nutr and Behav 1989; 3: 133–144.

    Google Scholar 

  9. Hill AJ, Blundell JE . Comparison of the action of macronutrients on the expression of appetite in lean and obese humans. Ann NY Acad Sci 1990; 575: 529–530.

    Google Scholar 

  10. Rolls BJ, Kim S, McNelis AL, Fischman MW, Foltin RW, Moran TH . Time course of effects of preloads high in fat or carbohydrate on food intake and hunger ratings in humans. Am Physiol Soc 1991; 260: R756–R763.

    CAS  Google Scholar 

  11. Barkeling B, Sc B, Granfelt Y, Bjorck I, Rossner S . Effects of carbohydrates in the form of pasta and bread on food intake and satiety in man. Pergamon 1995; 15: 467–476.

    Google Scholar 

  12. Stubbs RJ, van Wyk MCW, Johnstone AM, Harbron CG . Breakfasts high in protein, fat or carbohydrate: effect on within-day appetite and energy balance. Eur J Clin Nutr 1996; 50: 409–417.

    CAS  PubMed  Google Scholar 

  13. Vanderwater K, Vickers Z . Higher-protein foods produce greater sensory-specific satiety. Physiol Behav 1996; 59: 579–583.

    Google Scholar 

  14. Johnson J, Vickers Z . Effects of flavor and macronutrient composition of food servings on liking, hunger and subsequent intake. Appetite 1993; 21: 25–39.

    CAS  PubMed  Google Scholar 

  15. Poppitt SD, Eckhardt JW, McGonagle J, Murgatroyd PR, Prentice AM . Short-term effects of alcohol consumption on appetite and energy intake. Physiol Behav 1996; 60: 1063–1070.

    CAS  PubMed  Google Scholar 

  16. Lambert TC, Hill AJ, Blundell JE . Investigating the satiating effect of protein with disguised liquid preloads. Appetite 1989; 12: 220.

    Google Scholar 

  17. Latner JD, Schwartz M . The effects of a high-carbohydrate, high-protein or balanced lunch upon later food intake and hunger ratings. Appetite 1999; 33: 119–128.

    CAS  PubMed  Google Scholar 

  18. Driver CJI . The effect of meal composition on the degree of satiation following a test meal and possible mechanisms involved. Br J Nutr 1988; 60: 441–449.

    CAS  PubMed  Google Scholar 

  19. de Graaf C, Hulshof T, Westrate JA, Jas P . Short-term effects of different amounts of protein, fats, and carbohydrate in a midday meal. Am J Clin Nutr 1992; 55: 33–38.

    CAS  PubMed  Google Scholar 

  20. Stockley L, Jones FA, Broadhurst AJ . The effects of moderate protein or energy supplements on subsequent nutrient intake in man. Appetite 1984; 12: 209–219.

    Google Scholar 

  21. Sunkin S, Garrow JS . The satiety value of protein. Hum Nutr Appl Nutr 1982; 36A: 197–201.

    Google Scholar 

  22. Geliebter AA . Effects of equicaloric loads of protein, fat and carbohydrate on food intake in the rat and man. Physiol Behav 1979; 22: 267–273.

    CAS  PubMed  Google Scholar 

  23. Colditz GA, Giovannucci E, Rimm EB, Stampfer MJ, Rosner B, Speizer FE et al. Alcohol intake in relation to diet and obesity in women and men. Am J Clin Nutr 1991; 54: 49–55.

    CAS  PubMed  Google Scholar 

  24. Poppitt SD, Eckhardt JW, McGonagle J, Murgatroyd PR, Prentice AM . Short-term effects of alcohol consumption on appetite and energy intake. Physiol Behav 1996; 60: 1063–1070.

    CAS  PubMed  Google Scholar 

  25. Jacques PF, Sulsky S, Hartz SC, Russell RM . Moderate alcohol intake and nutritional status in nonalcoholic elderly subjects. Am J Clin Nutr 1989; 50: 875–883.

    CAS  PubMed  Google Scholar 

  26. De Castro JM, Orozco S . Moderate alcohol intake and spontaneous eating patterns of humans: evidence of unregulated supplementation. Am J Clin Nutr 1989; 50: 875–883.

    Google Scholar 

  27. Rose D, Murphy SP, Hudes M, Viteri FE . Food energy remains constant wit increasing alcohol intake. J Am Diet Assoc 1995; 95: 698–700.

    CAS  PubMed  Google Scholar 

  28. Tremblay A, Wouters E, Wenker M, St-Pierre S, Bouchard C, Despres J-P . Alcohol and a high fat diet: a combination favoring overfeeding. Am J Clin Nutr 1995; 62: 639–644.

    CAS  PubMed  Google Scholar 

  29. Hill AB . The environment and disease: association or causation? Proc R Soc Med 1965; 58: 295–300.

    CAS  PubMed Central  PubMed  Google Scholar 

  30. Raben A, Tagliabue A, Christensen NJ, Madsen J, Holst JJ, Astrup A . Resistant starch: the effect on postprandial glycemia, hormonal response, and satiety. Am J Clin Nutr 1994; 60: 544–551.

    CAS  PubMed  Google Scholar 

  31. Tournier A, Louis-Sylvestre J . Effect of the physical state of a food on subsequent intake in human subjects. Appetite 1991; 16: 17–24.

    CAS  PubMed  Google Scholar 

  32. Hulshof T, De Graaf C, Weststrate JA . The effects of preloads varying in physical state and fat content on satiety and energy intake. Appetite 1993; 21: 273–286.

    CAS  PubMed  Google Scholar 

  33. Porrini M, Crovetti R, Riso P, Santangelo A, Testolin G . Effects of physical and chemical characteristics of food on specific and general satiety. Physiol Behav 1995; 57: 461–468.

    CAS  PubMed  Google Scholar 

  34. Harnack L, Stang J, Story M . Soft drink consumption among US children and adolescents: nutritional consequences. J Am Diet Assoc 1999; 99: 436–441.

    CAS  PubMed  Google Scholar 

  35. Wharton MS, Hampl JS . Beverage consumption and risk of obesity among Native Americans in Arizona. Nutr Rev 2004; 62: 153–159.

    PubMed  Google Scholar 

  36. Bes-Rastrollo M, Sanchez-Villegas A, Gomez-Garcia E, Martinez JA, Pajares RM, Martinez-Gonzalez MA . Predictors of weight gain in a Mediterranean cohort: the Seguimiento Universidad de Navarra Study. Am J Clin Nutr 2006; 83: 362–370.

    CAS  PubMed  Google Scholar 

  37. Lee HHC, Gerrior SA, Smith JA . Energy, macronutrient, and food intakes in relation to energy compensation in consumers who drink different types of milk. Am J Clin Nutr 1998; 67: 616–623.

    CAS  PubMed  Google Scholar 

  38. Gillis LJ, Bar-Or O . Food away from home, sugar-sweetened drink consumption and juvenile obesity. J Am Col Nutr 2003; 22: 539–545.

    Google Scholar 

  39. Ludwig DS, Peterson KE, Gortmaker SL . Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis. Lancet 2001; 357: 505–508.

    CAS  PubMed  Google Scholar 

  40. Mrdjenovic G, Levitsky DA . Nutritional and energetic consequences of sweetened drink consumption in 6- to 13-year-old children. Pediatr 2003; 142: 604–610.

    Google Scholar 

  41. Berkey CS, Rockett HRH, Field AE, Gillman MW, Colditz GA . Sugar-added beverages and adolescent weight change. Obes Res 2004; 12: 778–788.

    PubMed  Google Scholar 

  42. Troiano RP, Briefel RR, Carroll MD, Bialostosky K . Energy and fat intakes of children and adolescents in the US: data from the National Health and Nutrition Examination Surveys. Am J Clin Nutr 2000; 72: 1343–1353.

    Google Scholar 

  43. Bandini LG, Vu D, Must A, Cyr H, Goldberg A, Dietz WH . Comparison of high-calorie, low-nutrient dense food consumption among obese and non-obese adolescents. Obes Res 1999; 7: 438–443.

    CAS  PubMed  Google Scholar 

  44. Rajeshwari R, Yang S-J, Nicklas TA, Berenson GS . Secular trendes in children's sweetened-beverage consumption (1973–1994): The Bogalusa Heart Study. J Am Dietet Assoc 2005; 105: 208–214.

    Google Scholar 

  45. DiMeglio DP, Mattes RD . Liquid versus solid carbohydrate: effects on food intake and body weight. Int J Obes Relat Metab Disord 2000; 24: 794–800.

    CAS  PubMed  Google Scholar 

  46. Striegel-Moore RH, Thompson D, Affenito SG, Franko DL, Obarzanek E, Barton BA et al. Correlates of beverage intake in adolescent girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr 2006; 148: 183–187.

    PubMed  Google Scholar 

  47. James J, Thomas P, Cavan D, Kerr D . Preventing childhood obesity by reducing consumption of carbonated drinks: cluster randomised controlled trial. BMJ 2004; 328: 1237–1239.

    PubMed Central  PubMed  Google Scholar 

  48. Ebbeling CB, Feldman HA, Osganian SK, Chomitz VR, Ellenbogen SJ, Ludwig DS . Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: a randomized, controlled pilot study. Pediatrics 2006; 117: 673–680.

    PubMed  Google Scholar 

  49. Raben A, Vasilaras TH, Moller AC, Astrup A . Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 20 wk of supplementation in overweight subjects. Am J Clin Nutr 2002; 76: 721–729.

    CAS  PubMed  Google Scholar 

  50. Colditz GA, Giovannucci E, Rimm EB, Stampfer MJ, Rosner B, Speizer FE et al. Alcohol intake in relation to diet and obesity in women and men. Am J Clin Nutr 1991; 54: 49–55.

    CAS  PubMed  Google Scholar 

  51. Rose D, Murphy SP, Hudes M, Viteri FE . Food energy remains constant with increasing alcohol intake. J Am Diet Assoc 1995; 95: 698–700.

    CAS  PubMed  Google Scholar 

  52. Nielsen SJ, Popkin BM . Changes in beverage intake between 1977 and 2001. Am J Prev Med 2004; 27: 205–210.

    PubMed  Google Scholar 

  53. Harnack LJ, Jeffery RW, Boutelle KN . Temporal trends in energy intake in the United States: an ecologic perspective. Am J Clin Nutr 2000; 71: 1478–1484.

    CAS  PubMed  Google Scholar 

  54. Davidson TL, Swithers SE . Food viscosity influences caloric intake compensation and body weight in rats. Obes Res 2005; 13: 537–544.

    PubMed  Google Scholar 

  55. Davidson TL, Swithers SE . A Pavlovian approach to the problem of obesity. Int J Obes Relat Metab Disord 2004; 28: 933–935.

    CAS  PubMed  Google Scholar 

  56. Mattes RD . Dietary compensation by humans for supplemental energy provided as ethanol or carbohydrate in fluids. Physiol Behav 1996; 59: 179–187.

    CAS  PubMed  Google Scholar 

  57. Tordoff MG, Alleva AM . Effect of drinking soda sweetened with aspartame or high-fructose corn syrup on food intake and body weight. Am J Clin Nutr 1990; 51: 963–969.

    CAS  PubMed  Google Scholar 

  58. Cutler DM, Glaeser EL, Shapiro JM . Why have Americans become more obese? J Econ Perspect 2003; 17: 93–118.

    Google Scholar 

  59. Wooley OW, Wooley SC, Dunham RB . Can calories be perceived and do they affect hunger in obese and nonobese humans? J Comp Physiol Psychol 1972; 80: 250–258.

    CAS  PubMed  Google Scholar 

  60. Mattes RD . Soup and satiety. Physiol Behav 2005; 83: 739–747.

    CAS  PubMed  Google Scholar 

  61. Sakata T, Yoshimatsu H . Homestatic maintenance regulated by hypothalamic neuronal histamine. Meth Find Exp Clin Pharmacol 1996; 17: 51–56.

    Google Scholar 

  62. Fujise T, Yoshimatsu H, Kurokawa M, Oohara A, Kang M, Nakata M et al. Satiation and masticatory function modulated by brain histamine in rats. PSEBM 1998; 217: 228–234.

    CAS  Google Scholar 

  63. Delgado-Aros S, Cremonini F, Castillo JE, Chial HJ, Burton DD, Ferber I et al. Independent influences of body mass and gastric volumes on satiation in humans. Gastroenterology 2004; 126: 432–440.

    PubMed  Google Scholar 

  64. Geliebter A, Westreich S, Gage D . Gastric distention by balloon and test-meal intake in obese and lean subjects. Am J Clin Nutr 1988; 48: 592–594.

    CAS  PubMed  Google Scholar 

  65. Hveem K, Jones KL, Chatterton BE, Horowitz M . Scintigraphic measurement of gastric emptying and ultrasonographic assessment of antral area: relation to appetite. Gut 1996; 38: 816–821.

    CAS  PubMed Central  PubMed  Google Scholar 

  66. Ellis P, Kendall CW, Ren Y, Parker C, Pacy J, Waldron K et al. Role of cell walls in the bioaccessability of lipids in almond seeds. Am J Clin Nutr 2004; 80: 604–613.

    CAS  PubMed  Google Scholar 

  67. Miles CW, Kelsay JL, Wong NP . Effect of dietary fiber on the metabolizable energy of human diets. J Nutr 1988; 118: 1075–1081.

    CAS  PubMed  Google Scholar 

  68. Wisker E, Feldheim W . Metabolizable energy of diets low or high in dietary fiber from fruits and vegetables when consumed by humans. J Nutr 1990; 120: 1331–1337.

    CAS  PubMed  Google Scholar 

  69. Birch LL, McPhee L, Sullivan S . Children's food intake following drinks sweetened with sucrose or aspartame, time course effects. Physiol Behav 1989; 45: 387–395.

    CAS  PubMed  Google Scholar 

  70. Birch LL, Fisher JO . Food intake regulation in children. Fat and sugar substitutes and intake. Ann NY Acad Sci 1997; 819: 194–220.

    CAS  PubMed  Google Scholar 

  71. Poppitt SD, McCormack D, Buffenstein R . Short-term effects of macronutrient preloads on appetite and energy intake in lean women. Physiol Behav 1998; 64: 279–285.

    CAS  PubMed  Google Scholar 

  72. Latner JD, Schwartz M . The effects of a high-carbohydrate, high-protein or balanced lunch upon later food intake and hunger ratings. Appetite 1999; 33: 119–128.

    CAS  PubMed  Google Scholar 

  73. Marmonier C, Chapelot D, Louis-Sylvestre J . Effects of macronutrient content and energy density of snacks consumed in a satiety on the onset of the next meal. Appetite 2000; 34: 161–168.

    CAS  PubMed  Google Scholar 

  74. Mattes RD . Hunger ratings are not a reliable proxy measure of food intake in humans. Appetite 1990; 15: 103–113.

    CAS  PubMed  Google Scholar 

  75. Mrdjenovic G, Levitsky DA . Nutritional and energetic consequences of sweetened drink consumption in 6- to 13-year-old children. Pediatr 2003; 142: 604–610.

    Google Scholar 

  76. Striegel-Moore RH, Thompson D, Affenito SG, Franko DL, Obarzanek E, Barton BA et al. Correlates of beverage intake in adolescent girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr 2006; 148: 183–187.

    PubMed  Google Scholar 

  77. James J et al. Preventing childhood obesity by reducing consumption of carbonated drinks: cluster randomised controlled trial. BMJ 2004; 328: 1237. (E-pub 23 April 2004).

    PubMed Central  PubMed  Google Scholar 

  78. Ebbeling CB, Feldman HA, Osganian SK, Chomitz VR, Ellenbogen SJ, Ludwig DS . Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: a randomized, controlled pilot study. Pediatrics 2006; 117: 673–680.

    PubMed  Google Scholar 

  79. Tordoff MG, Alleva AM . Effect of drinking soda sweetened with aspartame or high-fructose corn syrup on food intake and body weight. Am J Clin Nutr 1990; 51: 963–969.

    CAS  PubMed  Google Scholar 

  80. Almiron-Roig E, Drewnowski A . Hunger, thirst, and energy intakes following consumption of caloric beverages. Physiol Behav 2003; 79: 767–773.

    CAS  PubMed  Google Scholar 

  81. Almiron-Roig E SY, Flores SY, Drewnowski A . No difference in satiety or in subsequent energy intakes between a beverage and a solid food. Physiol Behav 2004; 82: 671–677.

    PubMed  Google Scholar 

  82. Almiron-Roig E, Chen Y, Drewnowski A . Liquid calories and the failure of satiety: how good is the evidence?. Obes Rev 2003; 4: 201–212.

    CAS  PubMed  Google Scholar 

  83. Hulshof T, De Graaf C, Weststrate JA . The effects of preloads varying in physical state and fat content on satiety and energy intake. Appetite 1993; 21: 273–286.

    CAS  PubMed  Google Scholar 

  84. Haber GB, Heaton KW, Murphy D, Burroughs LF . Depletion and disruption of dietary fibre; effects on satiety, plasma-glucose, and serum-insulin. Lancet 1977; 2: 679–682.

    CAS  PubMed  Google Scholar 

  85. Tournier A, Louis-Sylvestre J . Effect of the physical state of a food on subsequent intake in human subjects. Appetite 1991; 16: 17–24.

    CAS  PubMed  Google Scholar 

  86. Bolton RP, Heaton KW, Burroughs LF . The role of dietary fiber in satiety, glucose, and insulin; studies with fruit and fruit juice. J Clin Nutr 1981; 34: 211–217.

    CAS  Google Scholar 

  87. Chapman IM, Goble EA, Wittert GA, Morley JE, Horowitz M . Effect of intravenous glucose and euglycemic insulin infusions on short term satiety and food intake. Am J Physiol 1998; 274: R596–603.

    CAS  PubMed  Google Scholar 

  88. Jenkins DJ, Kendall CW, Augustin LS, Vuksan V . High-complex carbohydrate or lente carbohydrate foods? Am J Med 2002; 30: 30S–37S.

    Google Scholar 

  89. Alfenas RCG, Mattes RD . Influence of glycemic index/load on glycemic response, appetite and food intake in healthy humans. Diabetes Care 2005; 28: 2123–2129.

    PubMed  Google Scholar 

  90. Teff KL, Elliott SS, Tschop M, Kieffer TJ, Rader D, Heiman M et al. Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women. Clin Endocrinol Metab 2004; 89: 2963–2972.

    CAS  Google Scholar 

  91. Ludwig DS, Majzoub JA, Al-Zahrani A, Dallal GE, Blanco I, Roberts SB . High glycemic index foods, overeating, and obesity. Pediatrics 1999; 103: 1–6.

    Google Scholar 

  92. Kraly FS . Physiology of drinking elicited by eating. Psychol Rev 1984; 91: 478–490.

    CAS  PubMed  Google Scholar 

  93. Phillips PA, Rolls BJ, Ledingham JG, Morton JJ . Body fluid changes, thirst and drinking in man during free access to water. Physiol Behav 1984; 33: 357–363.

    CAS  PubMed  Google Scholar 

  94. Rolls BJ, Kim S, Federoff IC . Effects of drinks sweetened with sucrose or aspartame on hunger, thirst and food intake in men. Physiol Behav 1990; 48: 19–26.

    CAS  PubMed  Google Scholar 

  95. Engell D, Kramer M, Malafi T, Salomon M, Lesher L . Effects of effort and social modeling on drinking in humans. Appetite 1996; 26: 129–138.

    CAS  PubMed  Google Scholar 

  96. Durlach PJ, Elliman NA, Rogers PJ . Drinking while thirsty can lead to conditioned increases in consumption. Appetite 2002; 39: 119–125.

    CAS  PubMed  Google Scholar 

  97. Hampl JS, Heaton CLB, Taylor CA . Snacking patterns influence energy and nutrient intakes but not body mass index. J Hum Nutr Diet 2003; 16: 3–11.

    CAS  PubMed  Google Scholar 

  98. Wilk B, Bar-Or O . Effect of drink flavor and NaCl on voluntary drinking and hydration in boys exercising in the heat. J Appl Physiol 1996; 80: 1112–1117.

    CAS  PubMed  Google Scholar 

  99. Kraly FS . Eating provides important physiological signals for satiety and drinking. Physiol Behav 2004; 82: 49–52.

    CAS  PubMed  Google Scholar 

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Mattes, R. Beverages and positive energy balance: the menace is the medium. Int J Obes 30 (Suppl 3), S60–S65 (2006). https://doi.org/10.1038/sj.ijo.0803494

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