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Effect of 2-month detraining on body composition and insulin sensitivity in young female dancers

Abstract

Objective:

To investigate the effect of 2-month detraining on body composition and glucose tolerance for female collegiate dancers.

Design:

Longitudinal study of dancers who stopped their regular training for 2 months.

Subjects:

16 female collegiate dancers (age: 19.7±0.11 year, body mass index (BMI): 20.7±0.56 kg/m2).

Measurements:

BMI, waist-to-hip ratio (WHR), oral glucose tolerance test (OGTT), insulin response during OGTT, and blood lipids at baseline and after a 2-month detraining.

Results:

Glucose tolerance was not significantly affected by the detraining, but the fasted insulin and insulin levels during OGTT were significantly elevated. Fasted free fatty acid (FFA) and triglyceride levels were significantly elevated without change in cholesterol level. BMI was not significantly altered during this detraining period, but the waist circumference and WHR ratio were significantly elevated.

Conclusion:

Only a 2-month cessation of regular training in female dancers significantly elevated basal and postprandial insulin levels and triglycerides, and were associated with increased basal FFA. This result appears to be partly related to the increased central fatness but not body mass, indicating that the early development of obesity due to reduced physical activity may not necessarily reflect on weight status. A warning is thus warranted for those young women who depend on weight measurement for body fat status monitoring.

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References

  1. Kopelman PG . Obesity as a medical problem. Nature 2000; 404: 635–643.

    Article  CAS  Google Scholar 

  2. Ivy JL, Zderic TW, Fogt DL . Prevention and treatment of non-insulin-dependent diabetes mellitus. Exerc Sport Sci Rev 1999; 27: 1–35.

    Article  CAS  Google Scholar 

  3. Ravussin E, Lillioja S, Knowler WC, Christin L, Freymond D, Abbott WG et al. Reduced rate of energy expenditure as a risk factor for body weight. N Engl J Med 1988; 318: 467–472.

    Article  CAS  Google Scholar 

  4. Birnbaum MJ . Diabetes: dialogue between muscle and fat. Nature 2001; 409: 672–673.

    Article  CAS  Google Scholar 

  5. Lewis GF, Carpentier A, Adeli K, Giacca A . Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 2002; 23: 201–229.

    Article  CAS  Google Scholar 

  6. Reaven GM . Role of insulin resistance in human disease. Diabetes 1988; 37: 1595–1607.

    Article  CAS  Google Scholar 

  7. Facchini FS, Hua N, Abbasi F, Reaven GM . Insulin resistance as a predictor of age-related diseases. J Clin Endocrinol Metab 2001; 86: 3574–3578.

    Article  CAS  Google Scholar 

  8. Willett WC, Dietz WH, Colditz GA . Guidelines for healthy weight. New Eng J Med 1999; 341: 427–434.

    Article  CAS  Google Scholar 

  9. Alméras N, Lemieux S, Bouchard C, Tremblay A . Fat gain in female swimmers. Physiol Behav 1997; 61: 811–817.

    Article  Google Scholar 

  10. Lee WC, Chen JJ, Hunt D, Hou CW, Lai YC, Lin FC et al. Effects of hiking at altitude on body composition and insulin sensitivity in recovery drug addicts. Prev Med 2004; 39: 681–688.

    Article  CAS  Google Scholar 

  11. Arciero PJ, Smith DL, Calles-Escandon J . Effects of short-term inactivity on glucose tolerance, energy expenditure, and blood flow in trained subjects. J Appl Physiol 1998; 84: 1365–1373.

    Article  CAS  Google Scholar 

  12. Petibois C, Cassaigne A, Gin H, Deleris G . Lipid profile disorders induced by long-term cessation of physical activity in previously highly endurance-trained subjects. J Clin Endocrinol Metab 2004; 89: 3377–3384.

    Article  CAS  Google Scholar 

  13. Shulman GI . Cellular mechanisms of insulin resistance. J Clin Invest 2000; 106: 171–176.

    Article  CAS  Google Scholar 

  14. Boden G, Chen X, Ruiz J, White JV, Rossetti L . Mechanism of fatty acid induced inhibition of glucose uptake. J Clin Invest 1994; 93: 2438–2446.

    Article  CAS  Google Scholar 

  15. Chakley SM, Hettiarachchi M, Chisholm DJ, Kraegen EW . Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat. Metabolism 1998; 47: 1121–1126.

    Article  Google Scholar 

  16. Dresner A, Laurent D, Marcucci M, Griffin ME, Dufour S, Cline GW et al. Effects of free fatty acids on glucose transport and IRS-1 associated phosphatidylinositol 3-kinase activity. J Clin Invest 1999; 103: 253–259.

    Article  CAS  Google Scholar 

  17. Crespin SR, Greenough WB, Steinberg D . Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect. J Clin Invest 1973; 52: 1979–1984.

    Article  CAS  Google Scholar 

  18. Warnotte C, Gilon P, Nenquin M, Henquin JC . Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells. Diabetes 1994; 43: 703–711.

    Article  CAS  Google Scholar 

  19. DeFronzo RA, Jacot E, Jequier E, Maeder E, Wahren J, Felber JP . The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 1981; 30: 1000–1007.

    Article  CAS  Google Scholar 

  20. Dohm GL . Regulation of skeletal muscle GLUT-4 expression by exercise. J Appl Physiol 2002; 93: 782–787.

    Article  CAS  Google Scholar 

  21. McCoy M, Proietto J, Hargreves M . Effect of detraining on GLUT-4 protein in human skeletal muscle. J Appl Physiol 1994; 77: 1532–1536.

    Article  CAS  Google Scholar 

  22. Blundell JE, King NA . Effects of exercise on appetite control: loose coupling between energy expenditure and energy intake. Int J Obes Relat Metab Disord Suppl 1998; 22: S22–S29.

    Google Scholar 

  23. Greiwe JS, Holloszy JO, Semenkovich CF . Exercise induces lipoprotein lipase and GLUT-4 protein in muscle independent of adrenergic-receptor signaling. J Appl Physiol 2000; 89: 176–181.

    Article  CAS  Google Scholar 

  24. Ladu MJ, Kapsas H, Palmer WK . Regulation of lipoprotein lipase in muscle and adipose tissue during exercise. J Appl Physiol 1991; 71: 404–409.

    Article  CAS  Google Scholar 

  25. Seip RL, Semenkovich CF . Skeletal muscle lipoprotein lipase: molecular regulation and physiological effects in relation to exercise. Exerc Sport Sci Rev 1998; 26: 191–218.

    Article  CAS  Google Scholar 

  26. Simsolo RB, Ong JM, Kern PA . The regulation of adipose tissue and muscle lipoprotein lipase in runners by detraining. J Clin Invest 1993; 92: 2124–2130.

    Article  CAS  Google Scholar 

  27. Schalch DS, Kipnis DM . Abnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acids. J Clin Invest 1965; 44: 2010–2020.

    Article  CAS  Google Scholar 

  28. Kazumi T, Vranic M, Steiner G . Triglyceride kinetics: effects of dietary glucose, sucrose, or fructose alone or with hyperinsulinemia. Am J Physiol 1986; 250: E325–E330.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This study was partially supported by a research grant from the National Science Council, Republic of China, Grant Number NSC 93-2413-H-154-009.

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Correspondence to C-H Kuo.

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Chen, SY., Chen, SM., Chang, WH. et al. Effect of 2-month detraining on body composition and insulin sensitivity in young female dancers. Int J Obes 30, 40–44 (2006). https://doi.org/10.1038/sj.ijo.0803073

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