Figure 10 | International Journal of Obesity

Figure 10

From: Influence of a selective histamine H3 receptor antagonist on hypothalamic neural activity, food intake and body weight

Figure 10

Accumulated food intake and changes in body weight in old DIO rats after dosing with either vehicle or NNC 38-1049 at 0 and 3.5 h. Vehicle was given alone or in combination with a 25% food restriction, and NNC 38-1049 was given in doses of 2 × 10 or 2 × 20 mg/kg for 15 days. Data are means±s.e.m. (n=14–15) and statistical differences between means are marked as follows: *P<0.05, **P<0.01, ***P<0.001. The food intake for the restricted group was not tested.

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