Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Paper
  • Published:

Understanding the physiology of obesity: review of recent developments in obesity research


Knowledge of the genetic and regulatory factors that influence energy homeostasis is advancing rapidly. There is increased understanding of the molecular signals that reach the brain with information regarding the current state of energy balance, how those signals are detected by the brain, and key neuronal systems important in translating the information into efferent responses. The identification of molecules that control food intake has generated new targets for drug development in the treatment of obesity. In view of the complexities of the energy control system, therapeutic strategies that target only one site are likely to be less effective than those targeting two or more sites.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

Author information

Authors and Affiliations


Corresponding author

Correspondence to SC Woods.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Woods, S., Seeley, R. Understanding the physiology of obesity: review of recent developments in obesity research. Int J Obes 26 (Suppl 4), S8–S10 (2002).

Download citation

  • Published:

  • Issue Date:

  • DOI:


This article is cited by


Quick links