Abstract
Increased androgenicity as assessed by increased testosterone and decreased SHBG is strongly associated with an unfavorable body fat distribution and increased glucose and insulin concentrations and insulin resistance in both pre- and postmenopausal women. However, the temporal direction of the association between androgens and insulin is uncertain. In men, the association between SHBG and insulin levels is much weaker and is probably inverse.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Insulin Resistance in Type 1 Diabetes Mellitus and Its Association with Patient’s Micro- and Macrovascular Complications, Sex Hormones, and Other Clinical Data
Diabetes Therapy Open Access 02 December 2019
-
Gender-specific associations of serum sex hormone-binding globulin with features of metabolic syndrome in children
Diabetology & Metabolic Syndrome Open Access 08 March 2016
-
Low sex hormone-binding globulin is associated with hypertension: a cross-sectional study in a Swedish population
BMC Cardiovascular Disorders Open Access 18 April 2013
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Haffner, S. Sex hormones, obesity, fat distribution, type 2 diabetes and insulin resistance: epidemiological and clinical correlation. Int J Obes 24 (Suppl 2), S56–S58 (2000). https://doi.org/10.1038/sj.ijo.0801279
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.ijo.0801279
Keywords
This article is cited by
-
Insulin Resistance in Type 1 Diabetes Mellitus and Its Association with Patient’s Micro- and Macrovascular Complications, Sex Hormones, and Other Clinical Data
Diabetes Therapy (2020)
-
Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE)
Journal of Endocrinological Investigation (2019)
-
Gender-specific associations of serum sex hormone-binding globulin with features of metabolic syndrome in children
Diabetology & Metabolic Syndrome (2016)
-
Trace Element Levels in Congenital Hypogonadotrophic Hypogonadism
Biological Trace Element Research (2016)
-
Low sex hormone-binding globulin is associated with hypertension: a cross-sectional study in a Swedish population
BMC Cardiovascular Disorders (2013)
