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In-vivo quantitative hydrolipidic map of perirenal adipose tissue by chemical shift imaging at 4.7 Tesla

International Journal of Obesity volume 25, pages 457–461 (2001)Cite this article

Abstract

OBJECTIVE: In this work, chemical shift magnetic resonance imaging is used for in vivo quantitative evaluation of fat and water content in the perirenal white adipose tissue.

DESIGN AND MEASUREMENTS: Experiments were carried out on female Sprague–Dawley rats with a 4.7 T magnet. Fat and water fractions were computed pixel-by-pixel from the chemical shift selective images with an algorithm of reconstruction that allowed parametric maps (called hydrolipidic maps) to be produced with a pixel size of 625×625 µm.

RESULTS: Our findings indicate that, in the perirenal adipose tissue, the water content ranges between 15% and 20%, with slight differences between the ventral and dorsal portions, and between the left and right deposits. The mesenteric adipose tissue, observed for comparison, has a mean water content of 30%.

CONCLUSION: The present work demonstrates that methods based on magnetic resonance imaging can be useful tools for non-invasive in vivo quantitative mapping of the hydrolipidic content of adipose tissues.

International Journal of Obesity (2001) 25, 457–461

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Acknowledgements

This work was supported by grants from the Italian Ministry of University and Scientific Research (MURST), the Italian National Research Council (CNR) and the European Union (EU).

We are grateful to Dr Mauro Fedrigo for his help in numerical data processing.

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Authors and Affiliations

  1. Magnetic Resonance Laboratory, Institute of Human Anatomy and Histology, University of Verona, Verona, Italy

    E Lunati, P Marzola, E Nicolato & A Sbarbati

  2. INFM Unit, University of Pavia, Pavia, Italy

    E Lunati

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  1. E Lunati
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  2. P Marzola
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  4. A Sbarbati
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Correspondence to A Sbarbati.

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Lunati, E., Marzola, P., Nicolato, E. et al. In-vivo quantitative hydrolipidic map of perirenal adipose tissue by chemical shift imaging at 4.7 Tesla. Int J Obes 25, 457–461 (2001). https://doi.org/10.1038/sj.ijo.0801262

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