Artificial Immunity and Typhoid Fever

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    THE announcement by Metchnikoff of his beautiful theory of the “mechanism,” as it were, of immunity, which he conceives as dependent upon the activity of the phagocytes or migratory cells of the body in the presence of disease germs, has called forth an immense number of researches in this direction from all parts of the world. But whilst some bacteriologists are engaged upon studying critically the experimental evidence which can be adduced in support of this theory, others are busy with the practical side of the subject and are devoting themselves to the investigation of what substances are capable of conferring immunity upon animals towards any particular disease, and hardly a month passes without some contribution being made to this important inquiry.

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    Artificial Immunity and Typhoid Fever. Nature 48, 211–212 (1893) doi:10.1038/048211a0

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